BIOLOGICAL ACTIVITY OF CITRULLUS COLOCYNTHIS L EXTRACTS ON CULEX PIPIENS MOLETHUS AND MUSCA DOMESTICA

The two most hazardous vectors for humans are Culex pipiens molethus and Musca domestica. Several environmental health issues have emerged because of the overuse chemical pesticides. This study sought to determine efficacy aqueous, alcohol, oil extracts Citrullus colocynthis L. plant under in vitro conditions using different concentrations (0, 5, 10, 20 mg/mL) on various stages It also identify natural biological alternatives synthetic insecticides. current research revealed that adult juvenile mosquitoes house flies were considerably impacted by bitter melon. Concentrations demonstrated a distinct effect significantly outperformed control treatment after 24, 48, 72 hrs exposure. Compared other melon extracts, impact extract C. was superior. At dosage mg/ml, reduced hatchability increased mortality second fourth larval molethus. outcomes superiority influencing fly M. domestica with same previous (20, 10,5 egg productivity (22, 72, 89, 82%) third instar (66, 79, 71, 94, 82.88%) rates, as well pupae weight rates (0.10, 0.11, 0.100 mg). With help study's findings, we may suggest particularly extract, potentially effective measure against flies. These naturally occurring which do not contain any industrial chemicals, difficult insect they intended kill withstand. For aim understanding mechanism action these flies, numerous therapeutic insects future, more is necessary.